ParkinsonCanadaV1, Main, Exploration, bibRecord, 000004

Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease.

Identifieur interne : 000004 ( Main/Exploration ); précédent : 000003; suivant : 000005

Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease.

Auteurs : Susan H. Fox [Canada] ; Leonard Verhagen Metman [États-Unis] ; John G. Nutt [États-Unis] ; Matthew Brodsky [États-Unis] ; Stewart A. Factor [États-Unis] ; Anthony E. Lang [Canada] ; Laura E. Pope [États-Unis] ; Nadine Knowles [États-Unis] ; João Siffert [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2017.

RBID : pubmed:28370447

Abstract

Nondopaminergic pathways represent potential targets to treat levodopa-induced dyskinesia in Parkinson's disease (PD). This pilot-study (NCT01767129) examined the safety/efficacy of the sigma-1 receptor-agonist and glutamatergic/monoaminergic modulator, dextromethorphan plus quinidine (to inhibit rapid dextromethorphan metabolism), for treating levodopa-induced dyskinesia.

DOI: 10.1002/mds.26976
PubMed: 28370447

Affiliations:

Le document en format XML

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La maladie de Parkinson au Canada (serveur d'exploration)

Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease.

Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease.

Source :

Abstract

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	La maladie de Parkinson au Canada (serveur d'exploration)
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